The rarest combination of hair and eye color is red hair and blue eyes. This combination is found in only 1% of the world's population. People with this combination often have fair skin and freckles.
The combination of red hair and blue eyes is thought to have originated in Scandinavia. It is more common in people of Northern European descent. Red hair is caused by a mutation in the MC1R gene, which is responsible for producing melanin. Melanin is the pigment that gives hair, skin, and eyes their color. The mutation in the MC1R gene results in reduced production of melanin, which leads to red hair. Blue eyes are caused by a lack of melanin in the iris. The iris is the colored part of the eye. When there is little or no melanin in the iris, the eyes appear blue.
